Useful Links

NCBI - Litterature

EcoCyc- Genomes and genes

Galaxy - RNAseq data analysis

Target RNA - RNA-RNA interaction preductions

IDT - Oligonucleotides analysis

RNAfold - RNA secondary structure predictions

UCSC - RNAseq data visualisation

sRNATarBase - sRNA database

mFOLD - RNA secondary structure predictions

ExPaSy- Protein prediction and analysis tools



Carrier MC, Bourassa JS, Massé E. Cellular Homeostasis: A Small RNA at the Crossroads of Iron and Photosynthesis. Current Biology.
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Lalaouna D, Massé E. Cut in translation : ribosome-dependent mRNA decay. The EMBO Journal.
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Lalaouna D, Prévost K, Eyraud A, Massé E. Identification of unknown RNA partners using MAPS. Methods.
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Carrier MC, Lalaouna D, Massé, E. A game of tag: MAPS catches up on RNA interactomes. RNA Biology.
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Lalaouna D, Massé E. The spectrum of activity of the small RNA DsrA: not so narrow after all. Curr Genet.
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Lalaouna D, Massé E. Identification of sRNA interacting with a transcript of interest using MS2-affinity purification coupled with RNA sequencing (MAPS) technology. Genom Data
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Lalaouna D, Morissette A, Carrier MC, Massé E. DsrA regulatory RNA represses both hns and rbsD mRNAs through distinct mechanisms in Escherichia coli. Microbiol. 2015 Oct.
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Lalaouna D, Carrier MC, Massé E. The shock absorber: preventing sRNA transcriptional noise. Cell Cycle. 2015.
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Lalaouna D, Carrier MC, Semsey S, Brouard JS, Wang J, Wade JT, Massé E. A 3' external transcribed spacer in a tRNA transcript acts as a sponge for small RNAs to prevent transcriptional noise. Mol Cell. 2015 May 7.
| Abstract | PDF | | Selected by Faculty of 1000|


Benjamin JA, Masse E. The iron-sensing aconitase B binds its own mRNA to prevent sRNA-induced mRNA cleavage. Nucleic Acids Res 2014 Sept.
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Lalaouna D, Eyraud A, Chabelskaya S, Felden B, Massé E. Regulatory RNAs involved in bacterial antibiotic resistance. PLoS Pathog. 2014 Aug 28.
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Salvail H, Caron MP, Bélanger J, Massé E. Antagonistic functions between the RNA chaperone Hfq and an sRNA regulate sensitivity to the antibiotic colicin. EMBO J. 2013. | Abstract | PDF |

Lalaouna D, Simoneau-Roy M, Lafontaine D, Massé E. Regulatory RNAs and target mRNA decay in procaryotes. Biochim Biophys Acta. 2013. | Abstract | PDF |


Caron MP, Bastet L, Lussier A, Simoneau-Roy M, Massé E, Lafontaine DA. Dual-acting riboswitch control of translation initiation and mRNA decay. Proc Natl Acad Sci U S A. 2012 Nov 19 | Abstract | PDF | Highlight in Nature Reviews Microbiology|

Desnoyers G, Bouchard MP, Massé E. New insights into small RNA-dependent translational regulation in prokaryotes. Trends Genet. S0168-9525(12)00163-1. | Abstract | PDF |

Desnoyers G, Massé E. Activity of Small RNAs on the Stability of Targeted mRNAs In Vivo. Methods Mol Biol. 2012. 905:245-55. | Abstract |

Desnoyers G, Massé E. Noncanonical repression of translation initiation through small RNA recruitment of the RNA chaperone Hfq. Genes Dev. 2012. 26(7):726-39. | Abstract | PDF | Selected by Faculty of 1000|


Salvail H, Massé E. Regulating iron storage and metabolism with RNA: an overview of posttranscriptional controls of intracellular iron homeostasis. Wiley Interdiscip Rev RNA. 2011 Jul 25. doi: 10.1002/wrna.102. | Abstract | PDF |

Benjamin JA, Prévost K, Massé E. Remote control of mRNA cleavage by a small RNA. Cell Cycle. 2011 Jun 1;10(11) | Abstract | PDF |

Bastet L, Dubé A, Massé E, Lafontaine DA. New insights into riboswitch regulation mechanisms. Mol Microbiol. 2011. | Abstract | PDF |

Prévost, K., Desnoyers, G., Jacques, J.F. Lavoie, F., and Massé, E . Small RNA-induced mRNA degradation achieved through both translation block and activated cleavage . Genes Dev. 2011. | Abstract | PDF | Commentaries from Morita and Aiba |

# Lemay JF, # Desnoyers G., Blouin S., Heppell B., Bastet L., St-Pierre P., *Massé E ., and * Lafontaine D. Comparative study between transcriptionally- and translationally-acting adenine riboswitches reveals key differences in riboswitch regulatory mechanisms. PLoS Genetics. 2011. # Contribution égale. *Corresponding authors. | Abstract | PDF |


Salvail H, Lanthier-Bourbonnais P, Sobota JM, Caza M, Benjamin JA, Mendieta ME, Lépine F, Dozois CM, Imlay J, Massé E. A small RNA promotes siderophore production through transcriptional and metabolic remodeling. Proc Natl Acad Sci U S A. 2010. 107(34):15223-8. | Abstract | PDF | Selected by Faculty of 1000 |

Caron, M.P., Lafontaine, D. and Massé, E. Small RNA-mediated regulation at the level of the transcription stability. 2010. RNA biology. | Abstract | PDF |

Benjamin J.A., Desnoyers, G., Morissette, A., Salvail, H., and Massé E. 2010. Dealing with oxydative stress and iron starvation in microoganisms: an overview. CJPP. | Abstract | PDF |


*Semsey S., Benjamin J.A.M., Mitarai N., Krishna S., Csiszovszki Z., Sneppen K., and *Massé E. Dynamics of the recovery from sRNA-mediated gene silencing. Cell cycle. *Corresponding authors. | Abstract | PDF |

* † Mitarai N, † Benjamin JA, Krishna S, Semsey S, Csiszovski Z, * Massé E, and Sneppen K. Dynamic Features of Gene Expression Control by Small regulatory RNAs. P.N.A.S. † Contributed equally. | Abstract | PDF | Selected by Faculty of 1000|

Desnoyers G., Morissette A., Prévost K. and Massé E., "Small RNA-induced differential degradation of the polycistronic mRNA iscRSUA", EMBO J. | Abstract | PDF |



*Massé E. and Pawelek P.D. Iron as nutrient: strategies for iron acquisition and usage by pathogenic microorganisms. In "Iron Deficiency and Overload: From Basic Biology to Clinical Medicine". Shlomo Yehuda and David I. Mostofsky (Editors). *Corresponding author.



Prévost K, Salvail H, Desnoyers G., Jacques JF, Phaneuf E, Massé E, The small RNA RyhB activates the translation of shiA mRNA encoding a permease of shikimate, a compound involved in siderophore synthesis. Mol Microbiol. 2007, 64(5):1260-73.
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Massé E, Salvail H, Desnoyers G, Arguin M. : Small RNAs controlling iron metabolism. Curr Opin Microbiol. 2007, (2):1405.
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Jacques JF, Jang S, Prévost K, Desnoyers G, Desmarais M, Imlay J, Massé E. : RyhB small RNA modulates the free intracellular iron pool and is essential for normal growth during iron limitation in Escherichia coli. Mol Microbiol. 2006, 62(4):1181-90. 
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Semsey S, Andersson AM, Krishna S, Jensen MH, Massé E, Sneppen K., Genetic regulation of fluxes: iron homeostasis of Escherichia coli. Nucleic Acids Res. 2006;34(17):4960-7.
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Massé E, Vanderpool CK, Gottesman S. : Effect of RyhB small RNA on global iron use in Escherichia coli. J Bacteriol. 2005, 187(20):6962-71. 
| Abstract | PDF | Highlight in ASM news | Commentary in J. Bacteriol. |

Massé E, Arguin M. : Ironing out the problem: new mechanisms of iron homeostasis. Trends Biochem Sci. 2005, (8):462-8. 
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Massé E, Escorcia FE, Gottesman S. : Coupled degradation of a small regulatory RNA and its mRNA targets in Escherichia coli. Genes Dev. 2003, 17(19):2374-83. 
| Abstract | PDF | Perspective in Genes Dev. |

Massé E, Majdalani N, Gottesman S. Regulatory roles for small RNAs in bacteria. Curr Opin Microbiol. 2003 Apr;6(2):120-4.
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Drolet M, Broccoli S, Rallu F, Hraiky C, Fortin C, Massé E, Baaklini I. The problem of hypernegative supercoiling and R-loop formation in transcription. Front Biosci. 2003 Jan 1;8:d210-21. Review. | Abstract | PDF |



Massé E, Gottesman S. A small RNA regulates the expression of genes involved in iron metabolism in Escherichia coli. Proc Natl Acad Sci USA 2002, 99(7):4620-5. 
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Massé E, Drolet M. R-loop-dependent hypernegative supercoiling in Escherichia coli topA mutants preferentially occurs at low temperatures and correlates with growth inhibition. J Mol Biol. 1999 Nov 26;294(2):321-32. | Abstract | PDF |

Massé E, Drolet M. Escherichia coli DNA topoisomerase I inhibits R-loop formation by relaxing transcription-induced negative supercoiling. J Biol Chem. 1999 Jun 4;274(23):16659-64. | Abstract | PDF |

Massé E, Drolet M. Relaxation of transcription-induced negative supercoiling is an essential function of Escherichia coli DNA topoisomerase I. J Biol Chem. 1999 Jun 4;274(23):16654-8 | Abstract | PDF |



Massé E, Phoenix P, Drolet M. DNA topoisomerases regulate R-loop formation during transcription of the rrnB operon in Escherichia coli. J Biol Chem. 1997 May 9;272(19):12816-23. | Abstract | PDF |

Phoenix P, Raymond MA, Massé E, Drolet M. Roles of DNA topoisomerases in the regulation of R-loop formation in vitro. J Biol Chem. 1997 Jan 17;272(3):1473-9. | Abstract | PDF |



Drolet M, Phoenix P, Menzel R, Massé E, Liu LF, Crouch RJ. Overexpression of RNase H partially complements the growth defect of an Escherichia coli delta topA mutant: R-loop formation is a major problem in the absence of DNA topoisomerase I. Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3526-30. | Abstract | PDF |